The Oxford English dictionary defines "to run" as to "move at a speed faster than a walk, never having both or all the feet on the ground at the same time." There are a lot of other meanings and idiomatic uses of "to run," however, which are commonly used and with which you should make yourself familiar.
We will have young people to run the island.
Caption 48, Bishop Stanley - Island CherriesPlay Caption
Here "to run" means "to operate," in the sense of "to run a business."
No, I'm not going to run for president.Play Caption
If you "run" for a political position, it means you are campaigning to win an election.
When your oil is running out, could you imagine doing the next film.
Caption 62, Fast & Furious 5 - Opening night in ColognePlay Caption
The phrase "to run out" of something means your supply is getting low.
But President Bush's team could not have been more professional or more gracious in making sure we had a smooth transition so that we could hit the ground running.
Captions 19-21, Barack Obama - on Trump Presidential VictoryPlay Caption
The phrase "to hit the ground running" is a metaphor that means "to take immediate action." Here you can see another metaphor using "run", albeit here as a noun:
Yes, there are two paths you can go by, but in the long run
There's still time to change the road you're on.
Captions 1-2, Led Zeppelin - Stairway to HeavenPlay Caption
The phrase "in the long run" means "eventually" or "after a long period of time."